Restylane Refyne and Defyne are two of the newest fillers on the market. They provide natural looking results to laugh lines, and other lines that require movement. It allows you to maintain your facial expressions. Traditional fillers usually sit in a specific area to plump that area. Restylane Refyne and Defyne are Hulauronic fillers that are flexible. It will move with you so you still have complete and normal facial expression and movement but look fuller, i.e. nasolabial folds. If you have done mid-face filler and have some laugh lines, or lines around your chin/lip area, that still bug you -this is the product for you! $600/syringe - Lasts up to a year